Product Description

Lanflox Oral Solution is indicated for the treatment of infections caused by bacteria susceptible to enrofloxacin. Wherever possible, use should be based on susceptibility testing of the causative organism, and official national and regional antimicrobial policies should be taken into account. Fluoroquinolones are critically important antimicrobials and should be reserved for conditions that have responded poorly, or are expected to respond poorly, to other classes of antimicrobials.

For Chickens:

Treatment of infections caused by Mycoplasma gallisepticum

Treatment of infections caused by Mycoplasma synoviae

Treatment of infections caused by Avibacterium paragallinarum

Treatment of infections caused by Pasteurella multocida

For Turkeys:

Treatment of infections caused by Mycoplasma gallisepticum

Treatment of infections caused by Mycoplasma synoviae

Treatment of infections caused by Pasteurella multocida

Which Animals Can Use Lanflox Solution?

Lanflox Solution is licensed for use in chickens and turkeys only. It must not be used in birds producing eggs for human consumption, for prophylaxis, or in flocks where resistance or cross-resistance to (fluoro)quinolones is known to occur. The product is not licensed for use in any other species. Always use only under the direction of your vet.

Available Strengths & Sizes

Please order the specific pack size as directed on your veterinary prescription.

Not all pack sizes may be marketed. Shelf life after first opening: 3 months. Shelf life after dilution according to instructions: 24 hours — prepare fresh medicated water every day immediately before offering to birds.

Directions for Use

Lanflox Solution is a prescription medication and must be used exactly as directed by your veterinary surgeon. The solution is administered orally via the drinking water — it may be added directly to a header tank or supplied through a water-proportioner system. Before use, header tanks must be emptied, thoroughly cleaned, and filled with a known volume of clean water before adding the required amount of product; the resulting mixture should be stirred. Medicated water must be the only source of water available to birds throughout the treatment period. Medicated water must be prepared fresh every day, immediately before offering. Use appropriate calibrated dosing equipment. Treatment duration is 3 to 5 consecutive days; if no clinical improvement is achieved within 2 to 3 days, susceptibility testing should be repeated and alternative therapy considered. Refer to the dispensing label and product datasheet for full dosing calculations.

Contraindications

Source: SPC Section 4.3

Do not use in birds producing eggs for human consumption

Do not use for prophylaxis

Do not use when resistance or cross-resistance to (fluoro)quinolones is known to occur in the flock intended for treatment

Do not use in cases of hypersensitivity to the active substance (enrofloxacin) or to any of the excipients

Storage & Handling

No special storage conditions are required. Shelf life after first opening the immediate packaging: 3 months. Shelf life after dilution: 24 hours. Do not mix with any other veterinary medicinal product. Keep out of the sight and reach of children at all times.

Withdrawal periods:

Meat and offal — Chickens: 7 days

Meat and offal — Turkeys: 13 days

Not authorised for use in birds producing eggs for human consumption

Do not administer to layer replacement birds within 14 days of coming into lay

Important Warnings

Source: SPC Sections 4.4 & 4.5

Antimicrobial stewardship: Fluoroquinolones should be reserved for clinical conditions that have responded poorly, or are expected to respond poorly, to other classes of antimicrobials; wherever possible, use should be based on susceptibility testing; use deviating from SPC instructions may increase the prevalence of fluoroquinolone-resistant bacteria and decrease the effectiveness of treatment with other quinolones due to cross-resistance potential; official and local antimicrobial policies must be taken into account

Resistance monitoring: Since enrofloxacin was first authorised for use in poultry, there has been widespread reduction in susceptibility of E. coli to fluoroquinolones and emergence of resistant organisms; resistance has also been reported in Mycoplasma synoviae in the EU

Mycoplasma infections: Treatment of Mycoplasma spp. infections may not eradicate the organism

Clinical response monitoring: If no clinical improvement is achieved within 2 to 3 days, susceptibility testing should be repeated and alternative antimicrobial therapy should be considered

Drug interactions — antagonism: Concurrent use of enrofloxacin with other antimicrobials, tetracyclines, and macrolide antibiotics may result in antagonistic effects; avoid concurrent use

Drug interactions — reduced absorption: Absorption of enrofloxacin may be reduced if the product is administered together with substances containing magnesium or aluminium; high concentrations of calcium and magnesium in the water system may cause precipitation of enrofloxacin during intermediate dilution in dosing devices

Drug interactions — steroidal anti-inflammatories: Do not combine enrofloxacin with steroidal anti-inflammatory products

Precipitation: Increased influx of air into medicated drinking water may cause precipitation of enrofloxacin; avoid admixing

Dosing accuracy: Carefully calculate total body mass to be treated and total daily water consumption before each treatment; intake of medicated water depends on the age and clinical condition of birds, ambient temperature, and lighting regime — adjust concentration accordingly to ensure correct dosage

Human safety — Gloves required: Wear impervious gloves when handling the product; direct contact with the skin should be avoided as it may cause sensitisation, contact dermatitis, and hypersensitivity reactions

Human safety — Skin and eye contact: In case of skin or eye contact, rinse the affected area immediately with clean water; if irritation persists, seek medical attention

Human safety — Hypersensitivity: People with known hypersensitivity to fluoroquinolones should avoid contact with this product

Do not eat, drink, or smoke whilst using this product

Wash hands and exposed skin thoroughly after use

POM-V Prescription Notice

This product is a Prescription Only Medicine — Veterinary (POM-V). It may only be supplied by a veterinary surgeon or, when prescribed by a veterinary surgeon, by a pharmacist or SQP. A valid veterinary prescription is required before this product can be dispensed.

MA Number: Vm 32509/4002